This article is well worth a read, and speaks for itself. The broader question, so often unasked, is why is depression/anxiety so rampant among children and youth (above and beyond the medicalisation of normal human emotions that is a continuing trend as seen, for example, in the latest DSM)? The second, in light of the continued failure of “anti-depressants” in most clinical trials and meta-analysis, is what are the alternatives? Since they clearly benefit some people, do little/nothing for many, and have a highly adverse effect on others a re-analysis of old studies along with new studies to figure out “who” benefits would be valuable. Here we are getting into the realm of constitutional medicine and typologies – the idea that different types are more likely to benefit from certain treatment than others. Personalised and person-centred medicine, would greatly decrease the number of unnecessary anti-depressant prescriptions, decrease side-effects and costs, and provide benefits to those individuals for which they are effective.
It looked like there may have been “deliberate attempts to play down the adverse event profile,” one researcher said.